Cyclorin
Cyclorin Brand names, Cyclorin Analogs
- Cicloserina
- Closerin
- Closina
- Cyclomycin
- Cyclorin
- Cycloserin
- Cycloserine, D-
- D-CS
- D-Cycloserine
- D-Cycloserine synth. BP 88
- D-Cycloserine, synthetic
- D-Oxamicina
- D-Oxamycin
- DL-Cycloserine
- Farmiserina
- Farmiserine
- L-Cycloserine
- Micoserina
- Miroserina
- Miroseryn
- Novoserin
- Orientomycin
- Oxamicina
- Oxamycin
- Oxymycin
- Seromycin
- Tebemicina
- Tisomycin
- Wasserina
- alpha-Cycloserine
Cyclorin Brand Names Mixture
- No information avaliable
Cyclorin Chemical_Formula
C3H6N2O2
Cyclorin RX_link
No information avaliable
Cyclorin fda sheet
Cyclorin msds (material safety sheet)
Cyclorin Synthesis Reference
No information avaliable
Cyclorin Molecular Weight
102.092 g/mol
Cyclorin Melting Point
147 oC
Cyclorin H2O Solubility
Soluble
Cyclorin State
Solid
Cyclorin LogP
-1.631
Cyclorin Dosage Forms
Capsules (red and gray capsules, oral, 250mg)
Cyclorin Indication
Used in combination with up to 5 other drugs as a treatment for Mycobacterium avium complex (MAC) and is also used to treat tuberculosis (TB).
Cyclorin Pharmacology
Cycloserine, a broad-spectrum antibiotic, may be bactericidal or bacteriostatic, depending on its concentration at the site of infection and the susceptibility of the organism. Cycloserine works by blocking the formation of these peptidoglycans. By doing this the walls of the bacteria become weak and it results in the death of the bacteria
Cyclorin Absorption
Rapidly and almost completely absorbed (70 to 90%) from the gastrointestinal tract following oral administration.
Cyclorin side effects and Toxicity
Oral LD50 in mouse is 5290 mg/kg, and in rat is over 5000 mg/kg. Symptoms of a cycloserine overdose include drowsiness, confusion, headache, dizziness, irritability, numbness and tingling, difficulty speaking, paralysis, abnormal behavior, seizures, and unconsciousness.
Cyclorin Patient Information
Cyclorin Organisms Affected
Enteric bacteria and other eubacteria
