D-Cycloserine
D-Cycloserine Brand names, D-Cycloserine Analogs
- Cicloserina
- Closerin
- Closina
- Cyclomycin
- Cyclorin
- Cycloserin
- Cycloserine, D-
- D-CS
- D-Cycloserine
- D-Cycloserine synth. BP 88
- D-Cycloserine, synthetic
- D-Oxamicina
- D-Oxamycin
- DL-Cycloserine
- Farmiserina
- Farmiserine
- L-Cycloserine
- Micoserina
- Miroserina
- Miroseryn
- Novoserin
- Orientomycin
- Oxamicina
- Oxamycin
- Oxymycin
- Seromycin
- Tebemicina
- Tisomycin
- Wasserina
- alpha-Cycloserine
D-Cycloserine Brand Names Mixture
- No information avaliable
D-Cycloserine Chemical_Formula
C3H6N2O2
D-Cycloserine RX_link
No information avaliable
D-Cycloserine fda sheet
D-Cycloserine msds (material safety sheet)
D-Cycloserine Synthesis Reference
No information avaliable
D-Cycloserine Molecular Weight
102.092 g/mol
D-Cycloserine Melting Point
147 oC
D-Cycloserine H2O Solubility
Soluble
D-Cycloserine State
Solid
D-Cycloserine LogP
-1.631
D-Cycloserine Dosage Forms
Capsules (red and gray capsules, oral, 250mg)
D-Cycloserine Indication
Used in combination with up to 5 other drugs as a treatment for Mycobacterium avium complex (MAC) and is also used to treat tuberculosis (TB).
D-Cycloserine Pharmacology
Cycloserine, a broad-spectrum antibiotic, may be bactericidal or bacteriostatic, depending on its concentration at the site of infection and the susceptibility of the organism. Cycloserine works by blocking the formation of these peptidoglycans. By doing this the walls of the bacteria become weak and it results in the death of the bacteria
D-Cycloserine Absorption
Rapidly and almost completely absorbed (70 to 90%) from the gastrointestinal tract following oral administration.
D-Cycloserine side effects and Toxicity
Oral LD50 in mouse is 5290 mg/kg, and in rat is over 5000 mg/kg. Symptoms of a cycloserine overdose include drowsiness, confusion, headache, dizziness, irritability, numbness and tingling, difficulty speaking, paralysis, abnormal behavior, seizures, and unconsciousness.
D-Cycloserine Patient Information
D-Cycloserine Organisms Affected
Enteric bacteria and other eubacteria
