D-Oxamycin
D-Oxamycin Brand names, D-Oxamycin Analogs
- Cicloserina
- Closerin
- Closina
- Cyclomycin
- Cyclorin
- Cycloserin
- Cycloserine, D-
- D-CS
- D-Cycloserine
- D-Cycloserine synth. BP 88
- D-Cycloserine, synthetic
- D-Oxamicina
- D-Oxamycin
- DL-Cycloserine
- Farmiserina
- Farmiserine
- L-Cycloserine
- Micoserina
- Miroserina
- Miroseryn
- Novoserin
- Orientomycin
- Oxamicina
- Oxamycin
- Oxymycin
- Seromycin
- Tebemicina
- Tisomycin
- Wasserina
- alpha-Cycloserine
D-Oxamycin Brand Names Mixture
- No information avaliable
D-Oxamycin Chemical_Formula
C3H6N2O2
D-Oxamycin RX_link
No information avaliable
D-Oxamycin fda sheet
D-Oxamycin msds (material safety sheet)
D-Oxamycin Synthesis Reference
No information avaliable
D-Oxamycin Molecular Weight
102.092 g/mol
D-Oxamycin Melting Point
147 oC
D-Oxamycin H2O Solubility
Soluble
D-Oxamycin State
Solid
D-Oxamycin LogP
-1.631
D-Oxamycin Dosage Forms
Capsules (red and gray capsules, oral, 250mg)
D-Oxamycin Indication
Used in combination with up to 5 other drugs as a treatment for Mycobacterium avium complex (MAC) and is also used to treat tuberculosis (TB).
D-Oxamycin Pharmacology
Cycloserine, a broad-spectrum antibiotic, may be bactericidal or bacteriostatic, depending on its concentration at the site of infection and the susceptibility of the organism. Cycloserine works by blocking the formation of these peptidoglycans. By doing this the walls of the bacteria become weak and it results in the death of the bacteria
D-Oxamycin Absorption
Rapidly and almost completely absorbed (70 to 90%) from the gastrointestinal tract following oral administration.
D-Oxamycin side effects and Toxicity
Oral LD50 in mouse is 5290 mg/kg, and in rat is over 5000 mg/kg. Symptoms of a cycloserine overdose include drowsiness, confusion, headache, dizziness, irritability, numbness and tingling, difficulty speaking, paralysis, abnormal behavior, seizures, and unconsciousness.
D-Oxamycin Patient Information
D-Oxamycin Organisms Affected
Enteric bacteria and other eubacteria
