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Closerin Brand names, Closerin Analogs

Closerin Brand Names Mixture

  • No information avaliable

Closerin Chemical_Formula


Closerin RX_link

No information avaliable

Closerin fda sheet

Closerin msds (material safety sheet)

Closerin MSDS

Closerin Synthesis Reference

No information avaliable

Closerin Molecular Weight

102.092 g/mol

Closerin Melting Point

147 oC

Closerin H2O Solubility


Closerin State


Closerin LogP


Closerin Dosage Forms

Capsules (red and gray capsules, oral, 250mg)

Closerin Indication

Used in combination with up to 5 other drugs as a treatment for Mycobacterium avium complex (MAC) and is also used to treat tuberculosis (TB).

Closerin Pharmacology

Cycloserine, a broad-spectrum antibiotic, may be bactericidal or bacteriostatic, depending on its concentration at the site of infection and the susceptibility of the organism. Cycloserine works by blocking the formation of these peptidoglycans. By doing this the walls of the bacteria become weak and it results in the death of the bacteria

Closerin Absorption

Rapidly and almost completely absorbed (70 to 90%) from the gastrointestinal tract following oral administration.

Closerin side effects and Toxicity

Oral LD50 in mouse is 5290 mg/kg, and in rat is over 5000 mg/kg. Symptoms of a cycloserine overdose include drowsiness, confusion, headache, dizziness, irritability, numbness and tingling, difficulty speaking, paralysis, abnormal behavior, seizures, and unconsciousness.

Closerin Patient Information

Closerin Organisms Affected

Enteric bacteria and other eubacteria