Farmiserine
Brand names,
Farmiserine
Analogs
Farmiserine
Brand Names Mixture
Farmiserine
Chemical_Formula
C3H6N2O2
Farmiserine
RX_link
No information avaliable
Farmiserine
fda sheet
Farmiserine
msds (material safety sheet)
Farmiserine
Synthesis Reference
No information avaliable
Farmiserine
Molecular Weight
102.092 g/mol
Farmiserine
Melting Point
147 oC
Farmiserine
H2O Solubility
Soluble
Farmiserine
State
Solid
Farmiserine
LogP
-1.631
Farmiserine
Dosage Forms
Capsules (red and gray capsules, oral, 250mg)
Farmiserine
Indication
Used in combination with up to 5 other drugs as a treatment for Mycobacterium avium complex (MAC) and is also used to treat tuberculosis (TB).
Farmiserine
Pharmacology
Cycloserine, a broad-spectrum antibiotic, may be bactericidal or bacteriostatic, depending on its concentration at the site of infection and the susceptibility of the organism. Cycloserine works by blocking the formation of these peptidoglycans. By doing this the walls of the bacteria become weak and it results in the death of the bacteria
Farmiserine
Absorption
Rapidly and almost completely absorbed (70 to 90%) from the gastrointestinal tract following oral administration.
Farmiserine
side effects and Toxicity
Oral LD50 in mouse is 5290 mg/kg, and in rat is over 5000 mg/kg. Symptoms of a cycloserine overdose include drowsiness, confusion, headache, dizziness, irritability, numbness and tingling, difficulty speaking, paralysis, abnormal behavior, seizures, and unconsciousness.
Farmiserine
Patient Information
Farmiserine
Organisms Affected
Enteric bacteria and other eubacteria