Seromycin
Brand names,
Seromycin
Analogs
Seromycin
Brand Names Mixture
Seromycin
Chemical_Formula
C3H6N2O2
Seromycin
RX_link
No information avaliable
Seromycin
fda sheet
Seromycin
msds (material safety sheet)
Seromycin
Synthesis Reference
No information avaliable
Seromycin
Molecular Weight
102.092 g/mol
Seromycin
Melting Point
147 oC
Seromycin
H2O Solubility
Soluble
Seromycin
State
Solid
Seromycin
LogP
-1.631
Seromycin
Dosage Forms
Capsules (red and gray capsules, oral, 250mg)
Seromycin
Indication
Used in combination with up to 5 other drugs as a treatment for Mycobacterium avium complex (MAC) and is also used to treat tuberculosis (TB).
Seromycin
Pharmacology
Cycloserine, a broad-spectrum antibiotic, may be bactericidal or bacteriostatic, depending on its concentration at the site of infection and the susceptibility of the organism. Cycloserine works by blocking the formation of these peptidoglycans. By doing this the walls of the bacteria become weak and it results in the death of the bacteria
Seromycin
Absorption
Rapidly and almost completely absorbed (70 to 90%) from the gastrointestinal tract following oral administration.
Seromycin
side effects and Toxicity
Oral LD50 in mouse is 5290 mg/kg, and in rat is over 5000 mg/kg. Symptoms of a cycloserine overdose include drowsiness, confusion, headache, dizziness, irritability, numbness and tingling, difficulty speaking, paralysis, abnormal behavior, seizures, and unconsciousness.
Seromycin
Patient Information
Seromycin
Organisms Affected
Enteric bacteria and other eubacteria