Oxamicina
Brand names,
Oxamicina
Analogs
Oxamicina
Brand Names Mixture
Oxamicina
Chemical_Formula
C3H6N2O2
Oxamicina
RX_link
No information avaliable
Oxamicina
fda sheet
Oxamicina
msds (material safety sheet)
Oxamicina
Synthesis Reference
No information avaliable
Oxamicina
Molecular Weight
102.092 g/mol
Oxamicina
Melting Point
147 oC
Oxamicina
H2O Solubility
Soluble
Oxamicina
State
Solid
Oxamicina
LogP
-1.631
Oxamicina
Dosage Forms
Capsules (red and gray capsules, oral, 250mg)
Oxamicina
Indication
Used in combination with up to 5 other drugs as a treatment for Mycobacterium avium complex (MAC) and is also used to treat tuberculosis (TB).
Oxamicina
Pharmacology
Cycloserine, a broad-spectrum antibiotic, may be bactericidal or bacteriostatic, depending on its concentration at the site of infection and the susceptibility of the organism. Cycloserine works by blocking the formation of these peptidoglycans. By doing this the walls of the bacteria become weak and it results in the death of the bacteria
Oxamicina
Absorption
Rapidly and almost completely absorbed (70 to 90%) from the gastrointestinal tract following oral administration.
Oxamicina
side effects and Toxicity
Oral LD50 in mouse is 5290 mg/kg, and in rat is over 5000 mg/kg. Symptoms of a cycloserine overdose include drowsiness, confusion, headache, dizziness, irritability, numbness and tingling, difficulty speaking, paralysis, abnormal behavior, seizures, and unconsciousness.
Oxamicina
Patient Information
Oxamicina
Organisms Affected
Enteric bacteria and other eubacteria