Miroseryn
Brand names,
Miroseryn
Analogs
Miroseryn
Brand Names Mixture
Miroseryn
Chemical_Formula
C3H6N2O2
Miroseryn
RX_link
No information avaliable
Miroseryn
fda sheet
Miroseryn
msds (material safety sheet)
Miroseryn
Synthesis Reference
No information avaliable
Miroseryn
Molecular Weight
102.092 g/mol
Miroseryn
Melting Point
147 oC
Miroseryn
H2O Solubility
Soluble
Miroseryn
State
Solid
Miroseryn
LogP
-1.631
Miroseryn
Dosage Forms
Capsules (red and gray capsules, oral, 250mg)
Miroseryn
Indication
Used in combination with up to 5 other drugs as a treatment for Mycobacterium avium complex (MAC) and is also used to treat tuberculosis (TB).
Miroseryn
Pharmacology
Cycloserine, a broad-spectrum antibiotic, may be bactericidal or bacteriostatic, depending on its concentration at the site of infection and the susceptibility of the organism. Cycloserine works by blocking the formation of these peptidoglycans. By doing this the walls of the bacteria become weak and it results in the death of the bacteria
Miroseryn
Absorption
Rapidly and almost completely absorbed (70 to 90%) from the gastrointestinal tract following oral administration.
Miroseryn
side effects and Toxicity
Oral LD50 in mouse is 5290 mg/kg, and in rat is over 5000 mg/kg. Symptoms of a cycloserine overdose include drowsiness, confusion, headache, dizziness, irritability, numbness and tingling, difficulty speaking, paralysis, abnormal behavior, seizures, and unconsciousness.
Miroseryn
Patient Information
Miroseryn
Organisms Affected
Enteric bacteria and other eubacteria