Novoserin
Brand names,
Novoserin
Analogs
Novoserin
Brand Names Mixture
Novoserin
Chemical_Formula
C3H6N2O2
Novoserin
RX_link
No information avaliable
Novoserin
fda sheet
Novoserin
msds (material safety sheet)
Novoserin
Synthesis Reference
No information avaliable
Novoserin
Molecular Weight
102.092 g/mol
Novoserin
Melting Point
147 oC
Novoserin
H2O Solubility
Soluble
Novoserin
State
Solid
Novoserin
LogP
-1.631
Novoserin
Dosage Forms
Capsules (red and gray capsules, oral, 250mg)
Novoserin
Indication
Used in combination with up to 5 other drugs as a treatment for Mycobacterium avium complex (MAC) and is also used to treat tuberculosis (TB).
Novoserin
Pharmacology
Cycloserine, a broad-spectrum antibiotic, may be bactericidal or bacteriostatic, depending on its concentration at the site of infection and the susceptibility of the organism. Cycloserine works by blocking the formation of these peptidoglycans. By doing this the walls of the bacteria become weak and it results in the death of the bacteria
Novoserin
Absorption
Rapidly and almost completely absorbed (70 to 90%) from the gastrointestinal tract following oral administration.
Novoserin
side effects and Toxicity
Oral LD50 in mouse is 5290 mg/kg, and in rat is over 5000 mg/kg. Symptoms of a cycloserine overdose include drowsiness, confusion, headache, dizziness, irritability, numbness and tingling, difficulty speaking, paralysis, abnormal behavior, seizures, and unconsciousness.
Novoserin
Patient Information
Novoserin
Organisms Affected
Enteric bacteria and other eubacteria