D-Cycloserine synth. BP 88
Brand names,
D-Cycloserine synth. BP 88
Analogs
D-Cycloserine synth. BP 88
Brand Names Mixture
D-Cycloserine synth. BP 88
Chemical_Formula
C3H6N2O2
D-Cycloserine synth. BP 88
RX_link
No information avaliable
D-Cycloserine synth. BP 88
fda sheet
D-Cycloserine synth. BP 88
msds (material safety sheet)
D-Cycloserine synth. BP 88
Synthesis Reference
No information avaliable
D-Cycloserine synth. BP 88
Molecular Weight
102.092 g/mol
D-Cycloserine synth. BP 88
Melting Point
147 oC
D-Cycloserine synth. BP 88
H2O Solubility
Soluble
D-Cycloserine synth. BP 88
State
Solid
D-Cycloserine synth. BP 88
LogP
-1.631
D-Cycloserine synth. BP 88
Dosage Forms
Capsules (red and gray capsules, oral, 250mg)
D-Cycloserine synth. BP 88
Indication
Used in combination with up to 5 other drugs as a treatment for Mycobacterium avium complex (MAC) and is also used to treat tuberculosis (TB).
D-Cycloserine synth. BP 88
Pharmacology
Cycloserine, a broad-spectrum antibiotic, may be bactericidal or bacteriostatic, depending on its concentration at the site of infection and the susceptibility of the organism. Cycloserine works by blocking the formation of these peptidoglycans. By doing this the walls of the bacteria become weak and it results in the death of the bacteria
D-Cycloserine synth. BP 88
Absorption
Rapidly and almost completely absorbed (70 to 90%) from the gastrointestinal tract following oral administration.
D-Cycloserine synth. BP 88
side effects and Toxicity
Oral LD50 in mouse is 5290 mg/kg, and in rat is over 5000 mg/kg. Symptoms of a cycloserine overdose include drowsiness, confusion, headache, dizziness, irritability, numbness and tingling, difficulty speaking, paralysis, abnormal behavior, seizures, and unconsciousness.
D-Cycloserine synth. BP 88
Patient Information
D-Cycloserine synth. BP 88
Organisms Affected
Enteric bacteria and other eubacteria