Oxamycin
Brand names,
Oxamycin
Analogs
Oxamycin
Brand Names Mixture
Oxamycin
Chemical_Formula
C3H6N2O2
Oxamycin
RX_link
No information avaliable
Oxamycin
fda sheet
Oxamycin
msds (material safety sheet)
Oxamycin
Synthesis Reference
No information avaliable
Oxamycin
Molecular Weight
102.092 g/mol
Oxamycin
Melting Point
147 oC
Oxamycin
H2O Solubility
Soluble
Oxamycin
State
Solid
Oxamycin
LogP
-1.631
Oxamycin
Dosage Forms
Capsules (red and gray capsules, oral, 250mg)
Oxamycin
Indication
Used in combination with up to 5 other drugs as a treatment for Mycobacterium avium complex (MAC) and is also used to treat tuberculosis (TB).
Oxamycin
Pharmacology
Cycloserine, a broad-spectrum antibiotic, may be bactericidal or bacteriostatic, depending on its concentration at the site of infection and the susceptibility of the organism. Cycloserine works by blocking the formation of these peptidoglycans. By doing this the walls of the bacteria become weak and it results in the death of the bacteria
Oxamycin
Absorption
Rapidly and almost completely absorbed (70 to 90%) from the gastrointestinal tract following oral administration.
Oxamycin
side effects and Toxicity
Oral LD50 in mouse is 5290 mg/kg, and in rat is over 5000 mg/kg. Symptoms of a cycloserine overdose include drowsiness, confusion, headache, dizziness, irritability, numbness and tingling, difficulty speaking, paralysis, abnormal behavior, seizures, and unconsciousness.
Oxamycin
Patient Information
Oxamycin
Organisms Affected
Enteric bacteria and other eubacteria