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Closina Brand names, Closina Analogs

Closina Brand Names Mixture

  • No information avaliable

Closina Chemical_Formula


Closina RX_link

No information avaliable

Closina fda sheet

Closina msds (material safety sheet)

Closina MSDS

Closina Synthesis Reference

No information avaliable

Closina Molecular Weight

102.092 g/mol

Closina Melting Point

147 oC

Closina H2O Solubility


Closina State


Closina LogP


Closina Dosage Forms

Capsules (red and gray capsules, oral, 250mg)

Closina Indication

Used in combination with up to 5 other drugs as a treatment for Mycobacterium avium complex (MAC) and is also used to treat tuberculosis (TB).

Closina Pharmacology

Cycloserine, a broad-spectrum antibiotic, may be bactericidal or bacteriostatic, depending on its concentration at the site of infection and the susceptibility of the organism. Cycloserine works by blocking the formation of these peptidoglycans. By doing this the walls of the bacteria become weak and it results in the death of the bacteria

Closina Absorption

Rapidly and almost completely absorbed (70 to 90%) from the gastrointestinal tract following oral administration.

Closina side effects and Toxicity

Oral LD50 in mouse is 5290 mg/kg, and in rat is over 5000 mg/kg. Symptoms of a cycloserine overdose include drowsiness, confusion, headache, dizziness, irritability, numbness and tingling, difficulty speaking, paralysis, abnormal behavior, seizures, and unconsciousness.

Closina Patient Information

Closina Organisms Affected

Enteric bacteria and other eubacteria