Farmiserina
Brand names,
Farmiserina
Analogs
Farmiserina
Brand Names Mixture
Farmiserina
Chemical_Formula
C3H6N2O2
Farmiserina
RX_link
No information avaliable
Farmiserina
fda sheet
Farmiserina
msds (material safety sheet)
Farmiserina
Synthesis Reference
No information avaliable
Farmiserina
Molecular Weight
102.092 g/mol
Farmiserina
Melting Point
147 oC
Farmiserina
H2O Solubility
Soluble
Farmiserina
State
Solid
Farmiserina
LogP
-1.631
Farmiserina
Dosage Forms
Capsules (red and gray capsules, oral, 250mg)
Farmiserina
Indication
Used in combination with up to 5 other drugs as a treatment for Mycobacterium avium complex (MAC) and is also used to treat tuberculosis (TB).
Farmiserina
Pharmacology
Cycloserine, a broad-spectrum antibiotic, may be bactericidal or bacteriostatic, depending on its concentration at the site of infection and the susceptibility of the organism. Cycloserine works by blocking the formation of these peptidoglycans. By doing this the walls of the bacteria become weak and it results in the death of the bacteria
Farmiserina
Absorption
Rapidly and almost completely absorbed (70 to 90%) from the gastrointestinal tract following oral administration.
Farmiserina
side effects and Toxicity
Oral LD50 in mouse is 5290 mg/kg, and in rat is over 5000 mg/kg. Symptoms of a cycloserine overdose include drowsiness, confusion, headache, dizziness, irritability, numbness and tingling, difficulty speaking, paralysis, abnormal behavior, seizures, and unconsciousness.
Farmiserina
Patient Information
Farmiserina
Organisms Affected
Enteric bacteria and other eubacteria