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Cycloserin Brand names, Cycloserin Analogs

Cycloserin Brand Names Mixture

  • No information avaliable

Cycloserin Chemical_Formula

C3H6N2O2

Cycloserin RX_link

No information avaliable

Cycloserin fda sheet

Cycloserin msds (material safety sheet)

Cycloserin MSDS

Cycloserin Synthesis Reference

No information avaliable

Cycloserin Molecular Weight

102.092 g/mol

Cycloserin Melting Point

147 oC

Cycloserin H2O Solubility

Soluble

Cycloserin State

Solid

Cycloserin LogP

-1.631

Cycloserin Dosage Forms

Capsules (red and gray capsules, oral, 250mg)

Cycloserin Indication

Used in combination with up to 5 other drugs as a treatment for Mycobacterium avium complex (MAC) and is also used to treat tuberculosis (TB).

Cycloserin Pharmacology

Cycloserine, a broad-spectrum antibiotic, may be bactericidal or bacteriostatic, depending on its concentration at the site of infection and the susceptibility of the organism. Cycloserine works by blocking the formation of these peptidoglycans. By doing this the walls of the bacteria become weak and it results in the death of the bacteria

Cycloserin Absorption

Rapidly and almost completely absorbed (70 to 90%) from the gastrointestinal tract following oral administration.

Cycloserin side effects and Toxicity

Oral LD50 in mouse is 5290 mg/kg, and in rat is over 5000 mg/kg. Symptoms of a cycloserine overdose include drowsiness, confusion, headache, dizziness, irritability, numbness and tingling, difficulty speaking, paralysis, abnormal behavior, seizures, and unconsciousness.

Cycloserin Patient Information

Cycloserin Organisms Affected

Enteric bacteria and other eubacteria