Cycloserin
Cycloserin Brand names, Cycloserin Analogs
- Cicloserina
- Closerin
- Closina
- Cyclomycin
- Cyclorin
- Cycloserin
- Cycloserine, D-
- D-CS
- D-Cycloserine
- D-Cycloserine synth. BP 88
- D-Cycloserine, synthetic
- D-Oxamicina
- D-Oxamycin
- DL-Cycloserine
- Farmiserina
- Farmiserine
- L-Cycloserine
- Micoserina
- Miroserina
- Miroseryn
- Novoserin
- Orientomycin
- Oxamicina
- Oxamycin
- Oxymycin
- Seromycin
- Tebemicina
- Tisomycin
- Wasserina
- alpha-Cycloserine
Cycloserin Brand Names Mixture
- No information avaliable
Cycloserin Chemical_Formula
C3H6N2O2
Cycloserin RX_link
No information avaliable
Cycloserin fda sheet
Cycloserin msds (material safety sheet)
Cycloserin Synthesis Reference
No information avaliable
Cycloserin Molecular Weight
102.092 g/mol
Cycloserin Melting Point
147 oC
Cycloserin H2O Solubility
Soluble
Cycloserin State
Solid
Cycloserin LogP
-1.631
Cycloserin Dosage Forms
Capsules (red and gray capsules, oral, 250mg)
Cycloserin Indication
Used in combination with up to 5 other drugs as a treatment for Mycobacterium avium complex (MAC) and is also used to treat tuberculosis (TB).
Cycloserin Pharmacology
Cycloserine, a broad-spectrum antibiotic, may be bactericidal or bacteriostatic, depending on its concentration at the site of infection and the susceptibility of the organism. Cycloserine works by blocking the formation of these peptidoglycans. By doing this the walls of the bacteria become weak and it results in the death of the bacteria
Cycloserin Absorption
Rapidly and almost completely absorbed (70 to 90%) from the gastrointestinal tract following oral administration.
Cycloserin side effects and Toxicity
Oral LD50 in mouse is 5290 mg/kg, and in rat is over 5000 mg/kg. Symptoms of a cycloserine overdose include drowsiness, confusion, headache, dizziness, irritability, numbness and tingling, difficulty speaking, paralysis, abnormal behavior, seizures, and unconsciousness.
Cycloserin Patient Information
Cycloserin Organisms Affected
Enteric bacteria and other eubacteria
