Orientomycin
Orientomycin Brand names, Orientomycin Analogs
- Cicloserina
- Closerin
- Closina
- Cyclomycin
- Cyclorin
- Cycloserin
- Cycloserine, D-
- D-CS
- D-Cycloserine
- D-Cycloserine synth. BP 88
- D-Cycloserine, synthetic
- D-Oxamicina
- D-Oxamycin
- DL-Cycloserine
- Farmiserina
- Farmiserine
- L-Cycloserine
- Micoserina
- Miroserina
- Miroseryn
- Novoserin
- Orientomycin
- Oxamicina
- Oxamycin
- Oxymycin
- Seromycin
- Tebemicina
- Tisomycin
- Wasserina
- alpha-Cycloserine
Orientomycin Brand Names Mixture
- No information avaliable
Orientomycin Chemical_Formula
C3H6N2O2
Orientomycin RX_link
No information avaliable
Orientomycin fda sheet
Orientomycin msds (material safety sheet)
Orientomycin Synthesis Reference
No information avaliable
Orientomycin Molecular Weight
102.092 g/mol
Orientomycin Melting Point
147 oC
Orientomycin H2O Solubility
Soluble
Orientomycin State
Solid
Orientomycin LogP
-1.631
Orientomycin Dosage Forms
Capsules (red and gray capsules, oral, 250mg)
Orientomycin Indication
Used in combination with up to 5 other drugs as a treatment for Mycobacterium avium complex (MAC) and is also used to treat tuberculosis (TB).
Orientomycin Pharmacology
Cycloserine, a broad-spectrum antibiotic, may be bactericidal or bacteriostatic, depending on its concentration at the site of infection and the susceptibility of the organism. Cycloserine works by blocking the formation of these peptidoglycans. By doing this the walls of the bacteria become weak and it results in the death of the bacteria
Orientomycin Absorption
Rapidly and almost completely absorbed (70 to 90%) from the gastrointestinal tract following oral administration.
Orientomycin side effects and Toxicity
Oral LD50 in mouse is 5290 mg/kg, and in rat is over 5000 mg/kg. Symptoms of a cycloserine overdose include drowsiness, confusion, headache, dizziness, irritability, numbness and tingling, difficulty speaking, paralysis, abnormal behavior, seizures, and unconsciousness.
Orientomycin Patient Information
Orientomycin Organisms Affected
Enteric bacteria and other eubacteria
