Wasserina
Brand names,
Wasserina
Analogs
Wasserina
Brand Names Mixture
Wasserina
Chemical_Formula
C3H6N2O2
Wasserina
RX_link
No information avaliable
Wasserina
fda sheet
Wasserina
msds (material safety sheet)
Wasserina
Synthesis Reference
No information avaliable
Wasserina
Molecular Weight
102.092 g/mol
Wasserina
Melting Point
147 oC
Wasserina
H2O Solubility
Soluble
Wasserina
State
Solid
Wasserina
LogP
-1.631
Wasserina
Dosage Forms
Capsules (red and gray capsules, oral, 250mg)
Wasserina
Indication
Used in combination with up to 5 other drugs as a treatment for Mycobacterium avium complex (MAC) and is also used to treat tuberculosis (TB).
Wasserina
Pharmacology
Cycloserine, a broad-spectrum antibiotic, may be bactericidal or bacteriostatic, depending on its concentration at the site of infection and the susceptibility of the organism. Cycloserine works by blocking the formation of these peptidoglycans. By doing this the walls of the bacteria become weak and it results in the death of the bacteria
Wasserina
Absorption
Rapidly and almost completely absorbed (70 to 90%) from the gastrointestinal tract following oral administration.
Wasserina
side effects and Toxicity
Oral LD50 in mouse is 5290 mg/kg, and in rat is over 5000 mg/kg. Symptoms of a cycloserine overdose include drowsiness, confusion, headache, dizziness, irritability, numbness and tingling, difficulty speaking, paralysis, abnormal behavior, seizures, and unconsciousness.
Wasserina
Patient Information
Wasserina
Organisms Affected
Enteric bacteria and other eubacteria