Micoserina
Brand names,
Micoserina
Analogs
Micoserina
Brand Names Mixture
Micoserina
Chemical_Formula
C3H6N2O2
Micoserina
RX_link
No information avaliable
Micoserina
fda sheet
Micoserina
msds (material safety sheet)
Micoserina
Synthesis Reference
No information avaliable
Micoserina
Molecular Weight
102.092 g/mol
Micoserina
Melting Point
147 oC
Micoserina
H2O Solubility
Soluble
Micoserina
State
Solid
Micoserina
LogP
-1.631
Micoserina
Dosage Forms
Capsules (red and gray capsules, oral, 250mg)
Micoserina
Indication
Used in combination with up to 5 other drugs as a treatment for Mycobacterium avium complex (MAC) and is also used to treat tuberculosis (TB).
Micoserina
Pharmacology
Cycloserine, a broad-spectrum antibiotic, may be bactericidal or bacteriostatic, depending on its concentration at the site of infection and the susceptibility of the organism. Cycloserine works by blocking the formation of these peptidoglycans. By doing this the walls of the bacteria become weak and it results in the death of the bacteria
Micoserina
Absorption
Rapidly and almost completely absorbed (70 to 90%) from the gastrointestinal tract following oral administration.
Micoserina
side effects and Toxicity
Oral LD50 in mouse is 5290 mg/kg, and in rat is over 5000 mg/kg. Symptoms of a cycloserine overdose include drowsiness, confusion, headache, dizziness, irritability, numbness and tingling, difficulty speaking, paralysis, abnormal behavior, seizures, and unconsciousness.
Micoserina
Patient Information
Micoserina
Organisms Affected
Enteric bacteria and other eubacteria