Tebemicina
Brand names,
Tebemicina
Analogs
Tebemicina
Brand Names Mixture
Tebemicina
Chemical_Formula
C3H6N2O2
Tebemicina
RX_link
No information avaliable
Tebemicina
fda sheet
Tebemicina
msds (material safety sheet)
Tebemicina
Synthesis Reference
No information avaliable
Tebemicina
Molecular Weight
102.092 g/mol
Tebemicina
Melting Point
147 oC
Tebemicina
H2O Solubility
Soluble
Tebemicina
State
Solid
Tebemicina
LogP
-1.631
Tebemicina
Dosage Forms
Capsules (red and gray capsules, oral, 250mg)
Tebemicina
Indication
Used in combination with up to 5 other drugs as a treatment for Mycobacterium avium complex (MAC) and is also used to treat tuberculosis (TB).
Tebemicina
Pharmacology
Cycloserine, a broad-spectrum antibiotic, may be bactericidal or bacteriostatic, depending on its concentration at the site of infection and the susceptibility of the organism. Cycloserine works by blocking the formation of these peptidoglycans. By doing this the walls of the bacteria become weak and it results in the death of the bacteria
Tebemicina
Absorption
Rapidly and almost completely absorbed (70 to 90%) from the gastrointestinal tract following oral administration.
Tebemicina
side effects and Toxicity
Oral LD50 in mouse is 5290 mg/kg, and in rat is over 5000 mg/kg. Symptoms of a cycloserine overdose include drowsiness, confusion, headache, dizziness, irritability, numbness and tingling, difficulty speaking, paralysis, abnormal behavior, seizures, and unconsciousness.
Tebemicina
Patient Information
Tebemicina
Organisms Affected
Enteric bacteria and other eubacteria