Miroserina
Brand names,
Miroserina
Analogs
Miroserina
Brand Names Mixture
Miroserina
Chemical_Formula
C3H6N2O2
Miroserina
RX_link
No information avaliable
Miroserina
fda sheet
Miroserina
msds (material safety sheet)
Miroserina
Synthesis Reference
No information avaliable
Miroserina
Molecular Weight
102.092 g/mol
Miroserina
Melting Point
147 oC
Miroserina
H2O Solubility
Soluble
Miroserina
State
Solid
Miroserina
LogP
-1.631
Miroserina
Dosage Forms
Capsules (red and gray capsules, oral, 250mg)
Miroserina
Indication
Used in combination with up to 5 other drugs as a treatment for Mycobacterium avium complex (MAC) and is also used to treat tuberculosis (TB).
Miroserina
Pharmacology
Cycloserine, a broad-spectrum antibiotic, may be bactericidal or bacteriostatic, depending on its concentration at the site of infection and the susceptibility of the organism. Cycloserine works by blocking the formation of these peptidoglycans. By doing this the walls of the bacteria become weak and it results in the death of the bacteria
Miroserina
Absorption
Rapidly and almost completely absorbed (70 to 90%) from the gastrointestinal tract following oral administration.
Miroserina
side effects and Toxicity
Oral LD50 in mouse is 5290 mg/kg, and in rat is over 5000 mg/kg. Symptoms of a cycloserine overdose include drowsiness, confusion, headache, dizziness, irritability, numbness and tingling, difficulty speaking, paralysis, abnormal behavior, seizures, and unconsciousness.
Miroserina
Patient Information
Miroserina
Organisms Affected
Enteric bacteria and other eubacteria