Cicloserina
Cicloserina Brand names, Cicloserina Analogs
- Cicloserina
- Closerin
- Closina
- Cyclomycin
- Cyclorin
- Cycloserin
- Cycloserine, D-
- D-CS
- D-Cycloserine
- D-Cycloserine synth. BP 88
- D-Cycloserine, synthetic
- D-Oxamicina
- D-Oxamycin
- DL-Cycloserine
- Farmiserina
- Farmiserine
- L-Cycloserine
- Micoserina
- Miroserina
- Miroseryn
- Novoserin
- Orientomycin
- Oxamicina
- Oxamycin
- Oxymycin
- Seromycin
- Tebemicina
- Tisomycin
- Wasserina
- alpha-Cycloserine
Cicloserina Brand Names Mixture
- No information avaliable
Cicloserina Chemical_Formula
C3H6N2O2
Cicloserina RX_link
No information avaliable
Cicloserina fda sheet
Cicloserina msds (material safety sheet)
Cicloserina Synthesis Reference
No information avaliable
Cicloserina Molecular Weight
102.092 g/mol
Cicloserina Melting Point
147 oC
Cicloserina H2O Solubility
Soluble
Cicloserina State
Solid
Cicloserina LogP
-1.631
Cicloserina Dosage Forms
Capsules (red and gray capsules, oral, 250mg)
Cicloserina Indication
Used in combination with up to 5 other drugs as a treatment for Mycobacterium avium complex (MAC) and is also used to treat tuberculosis (TB).
Cicloserina Pharmacology
Cycloserine, a broad-spectrum antibiotic, may be bactericidal or bacteriostatic, depending on its concentration at the site of infection and the susceptibility of the organism. Cycloserine works by blocking the formation of these peptidoglycans. By doing this the walls of the bacteria become weak and it results in the death of the bacteria
Cicloserina Absorption
Rapidly and almost completely absorbed (70 to 90%) from the gastrointestinal tract following oral administration.
Cicloserina side effects and Toxicity
Oral LD50 in mouse is 5290 mg/kg, and in rat is over 5000 mg/kg. Symptoms of a cycloserine overdose include drowsiness, confusion, headache, dizziness, irritability, numbness and tingling, difficulty speaking, paralysis, abnormal behavior, seizures, and unconsciousness.
Cicloserina Patient Information
Cicloserina Organisms Affected
Enteric bacteria and other eubacteria
