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Cicloserina Brand names, Cicloserina Analogs

Cicloserina Brand Names Mixture

  • No information avaliable

Cicloserina Chemical_Formula

C3H6N2O2

Cicloserina RX_link

No information avaliable

Cicloserina fda sheet

Cicloserina msds (material safety sheet)

Cicloserina MSDS

Cicloserina Synthesis Reference

No information avaliable

Cicloserina Molecular Weight

102.092 g/mol

Cicloserina Melting Point

147 oC

Cicloserina H2O Solubility

Soluble

Cicloserina State

Solid

Cicloserina LogP

-1.631

Cicloserina Dosage Forms

Capsules (red and gray capsules, oral, 250mg)

Cicloserina Indication

Used in combination with up to 5 other drugs as a treatment for Mycobacterium avium complex (MAC) and is also used to treat tuberculosis (TB).

Cicloserina Pharmacology

Cycloserine, a broad-spectrum antibiotic, may be bactericidal or bacteriostatic, depending on its concentration at the site of infection and the susceptibility of the organism. Cycloserine works by blocking the formation of these peptidoglycans. By doing this the walls of the bacteria become weak and it results in the death of the bacteria

Cicloserina Absorption

Rapidly and almost completely absorbed (70 to 90%) from the gastrointestinal tract following oral administration.

Cicloserina side effects and Toxicity

Oral LD50 in mouse is 5290 mg/kg, and in rat is over 5000 mg/kg. Symptoms of a cycloserine overdose include drowsiness, confusion, headache, dizziness, irritability, numbness and tingling, difficulty speaking, paralysis, abnormal behavior, seizures, and unconsciousness.

Cicloserina Patient Information

Cicloserina Organisms Affected

Enteric bacteria and other eubacteria