D-CS
D-CS Brand names, D-CS Analogs
- Cicloserina
- Closerin
- Closina
- Cyclomycin
- Cyclorin
- Cycloserin
- Cycloserine, D-
- D-CS
- D-Cycloserine
- D-Cycloserine synth. BP 88
- D-Cycloserine, synthetic
- D-Oxamicina
- D-Oxamycin
- DL-Cycloserine
- Farmiserina
- Farmiserine
- L-Cycloserine
- Micoserina
- Miroserina
- Miroseryn
- Novoserin
- Orientomycin
- Oxamicina
- Oxamycin
- Oxymycin
- Seromycin
- Tebemicina
- Tisomycin
- Wasserina
- alpha-Cycloserine
D-CS Brand Names Mixture
- No information avaliable
D-CS Chemical_Formula
C3H6N2O2
D-CS RX_link
No information avaliable
D-CS fda sheet
D-CS msds (material safety sheet)
D-CS Synthesis Reference
No information avaliable
D-CS Molecular Weight
102.092 g/mol
D-CS Melting Point
147 oC
D-CS H2O Solubility
Soluble
D-CS State
Solid
D-CS LogP
-1.631
D-CS Dosage Forms
Capsules (red and gray capsules, oral, 250mg)
D-CS Indication
Used in combination with up to 5 other drugs as a treatment for Mycobacterium avium complex (MAC) and is also used to treat tuberculosis (TB).
D-CS Pharmacology
Cycloserine, a broad-spectrum antibiotic, may be bactericidal or bacteriostatic, depending on its concentration at the site of infection and the susceptibility of the organism. Cycloserine works by blocking the formation of these peptidoglycans. By doing this the walls of the bacteria become weak and it results in the death of the bacteria
D-CS Absorption
Rapidly and almost completely absorbed (70 to 90%) from the gastrointestinal tract following oral administration.
D-CS side effects and Toxicity
Oral LD50 in mouse is 5290 mg/kg, and in rat is over 5000 mg/kg. Symptoms of a cycloserine overdose include drowsiness, confusion, headache, dizziness, irritability, numbness and tingling, difficulty speaking, paralysis, abnormal behavior, seizures, and unconsciousness.
D-CS Patient Information
D-CS Organisms Affected
Enteric bacteria and other eubacteria
