D-Cycloserine, synthetic
D-Cycloserine, synthetic Brand names, D-Cycloserine, synthetic Analogs
- Cicloserina
- Closerin
- Closina
- Cyclomycin
- Cyclorin
- Cycloserin
- Cycloserine, D-
- D-CS
- D-Cycloserine
- D-Cycloserine synth. BP 88
- D-Cycloserine, synthetic
- D-Oxamicina
- D-Oxamycin
- DL-Cycloserine
- Farmiserina
- Farmiserine
- L-Cycloserine
- Micoserina
- Miroserina
- Miroseryn
- Novoserin
- Orientomycin
- Oxamicina
- Oxamycin
- Oxymycin
- Seromycin
- Tebemicina
- Tisomycin
- Wasserina
- alpha-Cycloserine
D-Cycloserine, synthetic Brand Names Mixture
- No information avaliable
D-Cycloserine, synthetic Chemical_Formula
C3H6N2O2
D-Cycloserine, synthetic RX_link
No information avaliable
D-Cycloserine, synthetic fda sheet
D-Cycloserine, synthetic msds (material safety sheet)
D-Cycloserine, synthetic Synthesis Reference
No information avaliable
D-Cycloserine, synthetic Molecular Weight
102.092 g/mol
D-Cycloserine, synthetic Melting Point
147 oC
D-Cycloserine, synthetic H2O Solubility
Soluble
D-Cycloserine, synthetic State
Solid
D-Cycloserine, synthetic LogP
-1.631
D-Cycloserine, synthetic Dosage Forms
Capsules (red and gray capsules, oral, 250mg)
D-Cycloserine, synthetic Indication
Used in combination with up to 5 other drugs as a treatment for Mycobacterium avium complex (MAC) and is also used to treat tuberculosis (TB).
D-Cycloserine, synthetic Pharmacology
Cycloserine, a broad-spectrum antibiotic, may be bactericidal or bacteriostatic, depending on its concentration at the site of infection and the susceptibility of the organism. Cycloserine works by blocking the formation of these peptidoglycans. By doing this the walls of the bacteria become weak and it results in the death of the bacteria
D-Cycloserine, synthetic Absorption
Rapidly and almost completely absorbed (70 to 90%) from the gastrointestinal tract following oral administration.
D-Cycloserine, synthetic side effects and Toxicity
Oral LD50 in mouse is 5290 mg/kg, and in rat is over 5000 mg/kg. Symptoms of a cycloserine overdose include drowsiness, confusion, headache, dizziness, irritability, numbness and tingling, difficulty speaking, paralysis, abnormal behavior, seizures, and unconsciousness.
D-Cycloserine, synthetic Patient Information
D-Cycloserine, synthetic Organisms Affected
Enteric bacteria and other eubacteria
