Cycloserine
Cycloserine Brand names, Cycloserine Analogs
- Cicloserina
- Closerin
- Closina
- Cyclomycin
- Cyclorin
- Cycloserin
- Cycloserine, D-
- D-CS
- D-Cycloserine
- D-Cycloserine synth. BP 88
- D-Cycloserine, synthetic
- D-Oxamicina
- D-Oxamycin
- DL-Cycloserine
- Farmiserina
- Farmiserine
- L-Cycloserine
- Micoserina
- Miroserina
- Miroseryn
- Novoserin
- Orientomycin
- Oxamicina
- Oxamycin
- Oxymycin
- Seromycin
- Tebemicina
- Tisomycin
- Wasserina
- alpha-Cycloserine
Cycloserine Brand Names Mixture
- No information avaliable
Cycloserine Chemical_Formula
C3H6N2O2
Cycloserine RX_link
No information avaliable
Cycloserine fda sheet
Cycloserine msds (material safety sheet)
Cycloserine Synthesis Reference
No information avaliable
Cycloserine Molecular Weight
102.092 g/mol
Cycloserine Melting Point
147 oC
Cycloserine H2O Solubility
Soluble
Cycloserine State
Solid
Cycloserine LogP
-1.631
Cycloserine Dosage Forms
Capsules (red and gray capsules, oral, 250mg)
Cycloserine Indication
Used in combination with up to 5 other drugs as a treatment for Mycobacterium avium complex (MAC) and is also used to treat tuberculosis (TB).
Cycloserine Pharmacology
Cycloserine, a broad-spectrum antibiotic, may be bactericidal or bacteriostatic, depending on its concentration at the site of infection and the susceptibility of the organism. Cycloserine works by blocking the formation of these peptidoglycans. By doing this the walls of the bacteria become weak and it results in the death of the bacteria
Cycloserine Absorption
Rapidly and almost completely absorbed (70 to 90%) from the gastrointestinal tract following oral administration.
Cycloserine side effects and Toxicity
Oral LD50 in mouse is 5290 mg/kg, and in rat is over 5000 mg/kg. Symptoms of a cycloserine overdose include drowsiness, confusion, headache, dizziness, irritability, numbness and tingling, difficulty speaking, paralysis, abnormal behavior, seizures, and unconsciousness.
Cycloserine Patient Information
Cycloserine Organisms Affected
Enteric bacteria and other eubacteria
