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Oxcord Brand names, Oxcord Analogs

Oxcord Brand Names Mixture

  • No information avaliable

Oxcord Chemical_Formula

C17H18N2O6

Oxcord RX_link

http://www.rxlist.com/cgi/generic2/nifedip.htm

Oxcord fda sheet

Oxcord FDA

Oxcord msds (material safety sheet)

Oxcord MSDS

Oxcord Synthesis Reference

Bossert, Vater, U.S. Pat. 3,485,847 (1969)

Oxcord Molecular Weight

346.335 g/mol

Oxcord Melting Point

172 - 174 oC

Oxcord H2O Solubility

Insoluble

Oxcord State

Solid

Oxcord LogP

2.343

Oxcord Dosage Forms

Capsule; Tablet; Tablet (extended-release)

Oxcord Indication

For the management of vasospastic angina, chronic stable angina and hypertension.

Oxcord Pharmacology

Nifedipine, the prototype of the dihydropyridine class of calcium-channel antagonists, is similar to other dihydropyridines including amlodipine, felodipine, isradipine, and nicardipine. Nifedipine is used to treat Prinzmetal's angina, hypertension, and other vascular disorders such as Raynaud's phenomenon. By blocking the calcium channels, Nifedipine inhibits the spasm of the coronary artery and dilates the systemic arteries, results in a increase of myocardial oxygen supply and a decrease in systemic blood pressure.

Oxcord Absorption

Rapidly and fully absorbed following oral administration.

Oxcord side effects and Toxicity

Symptoms of overdose include dizziness, drowsiness, nausea, severe drop in blood pressure, slurred speech, and weakness. LD50=494 mg/kg (orally in mice); LD50=1022 mg/kg (orally in rats)

Oxcord Patient Information

Oxcord Organisms Affected

Humans and other mammals