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Introcar Brand names, Introcar Analogs

Introcar Brand Names Mixture

  • No information avaliable

Introcar Chemical_Formula

C17H18N2O6

Introcar RX_link

http://www.rxlist.com/cgi/generic2/nifedip.htm

Introcar fda sheet

Introcar FDA

Introcar msds (material safety sheet)

Introcar MSDS

Introcar Synthesis Reference

Bossert, Vater, U.S. Pat. 3,485,847 (1969)

Introcar Molecular Weight

346.335 g/mol

Introcar Melting Point

172 - 174 oC

Introcar H2O Solubility

Insoluble

Introcar State

Solid

Introcar LogP

2.343

Introcar Dosage Forms

Capsule; Tablet; Tablet (extended-release)

Introcar Indication

For the management of vasospastic angina, chronic stable angina and hypertension.

Introcar Pharmacology

Nifedipine, the prototype of the dihydropyridine class of calcium-channel antagonists, is similar to other dihydropyridines including amlodipine, felodipine, isradipine, and nicardipine. Nifedipine is used to treat Prinzmetal's angina, hypertension, and other vascular disorders such as Raynaud's phenomenon. By blocking the calcium channels, Nifedipine inhibits the spasm of the coronary artery and dilates the systemic arteries, results in a increase of myocardial oxygen supply and a decrease in systemic blood pressure.

Introcar Absorption

Rapidly and fully absorbed following oral administration.

Introcar side effects and Toxicity

Symptoms of overdose include dizziness, drowsiness, nausea, severe drop in blood pressure, slurred speech, and weakness. LD50=494 mg/kg (orally in mice); LD50=1022 mg/kg (orally in rats)

Introcar Patient Information

Introcar Organisms Affected

Humans and other mammals