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Fenihidine Brand names, Fenihidine Analogs

Fenihidine Brand Names Mixture

  • No information avaliable

Fenihidine Chemical_Formula

C17H18N2O6

Fenihidine RX_link

http://www.rxlist.com/cgi/generic2/nifedip.htm

Fenihidine fda sheet

Fenihidine FDA

Fenihidine msds (material safety sheet)

Fenihidine MSDS

Fenihidine Synthesis Reference

Bossert, Vater, U.S. Pat. 3,485,847 (1969)

Fenihidine Molecular Weight

346.335 g/mol

Fenihidine Melting Point

172 - 174 oC

Fenihidine H2O Solubility

Insoluble

Fenihidine State

Solid

Fenihidine LogP

2.343

Fenihidine Dosage Forms

Capsule; Tablet; Tablet (extended-release)

Fenihidine Indication

For the management of vasospastic angina, chronic stable angina and hypertension.

Fenihidine Pharmacology

Nifedipine, the prototype of the dihydropyridine class of calcium-channel antagonists, is similar to other dihydropyridines including amlodipine, felodipine, isradipine, and nicardipine. Nifedipine is used to treat Prinzmetal's angina, hypertension, and other vascular disorders such as Raynaud's phenomenon. By blocking the calcium channels, Nifedipine inhibits the spasm of the coronary artery and dilates the systemic arteries, results in a increase of myocardial oxygen supply and a decrease in systemic blood pressure.

Fenihidine Absorption

Rapidly and fully absorbed following oral administration.

Fenihidine side effects and Toxicity

Symptoms of overdose include dizziness, drowsiness, nausea, severe drop in blood pressure, slurred speech, and weakness. LD50=494 mg/kg (orally in mice); LD50=1022 mg/kg (orally in rats)

Fenihidine Patient Information

Fenihidine Organisms Affected

Humans and other mammals