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Dilcor Brand names, Dilcor Analogs

Dilcor Brand Names Mixture

  • No information avaliable

Dilcor Chemical_Formula

C17H18N2O6

Dilcor RX_link

http://www.rxlist.com/cgi/generic2/nifedip.htm

Dilcor fda sheet

Dilcor FDA

Dilcor msds (material safety sheet)

Dilcor MSDS

Dilcor Synthesis Reference

Bossert, Vater, U.S. Pat. 3,485,847 (1969)

Dilcor Molecular Weight

346.335 g/mol

Dilcor Melting Point

172 - 174 oC

Dilcor H2O Solubility

Insoluble

Dilcor State

Solid

Dilcor LogP

2.343

Dilcor Dosage Forms

Capsule; Tablet; Tablet (extended-release)

Dilcor Indication

For the management of vasospastic angina, chronic stable angina and hypertension.

Dilcor Pharmacology

Nifedipine, the prototype of the dihydropyridine class of calcium-channel antagonists, is similar to other dihydropyridines including amlodipine, felodipine, isradipine, and nicardipine. Nifedipine is used to treat Prinzmetal's angina, hypertension, and other vascular disorders such as Raynaud's phenomenon. By blocking the calcium channels, Nifedipine inhibits the spasm of the coronary artery and dilates the systemic arteries, results in a increase of myocardial oxygen supply and a decrease in systemic blood pressure.

Dilcor Absorption

Rapidly and fully absorbed following oral administration.

Dilcor side effects and Toxicity

Symptoms of overdose include dizziness, drowsiness, nausea, severe drop in blood pressure, slurred speech, and weakness. LD50=494 mg/kg (orally in mice); LD50=1022 mg/kg (orally in rats)

Dilcor Patient Information

Dilcor Organisms Affected

Humans and other mammals