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Zenusin Brand names, Zenusin Analogs

Zenusin Brand Names Mixture

  • No information avaliable

Zenusin Chemical_Formula

C17H18N2O6

Zenusin RX_link

http://www.rxlist.com/cgi/generic2/nifedip.htm

Zenusin fda sheet

Zenusin FDA

Zenusin msds (material safety sheet)

Zenusin MSDS

Zenusin Synthesis Reference

Bossert, Vater, U.S. Pat. 3,485,847 (1969)

Zenusin Molecular Weight

346.335 g/mol

Zenusin Melting Point

172 - 174 oC

Zenusin H2O Solubility

Insoluble

Zenusin State

Solid

Zenusin LogP

2.343

Zenusin Dosage Forms

Capsule; Tablet; Tablet (extended-release)

Zenusin Indication

For the management of vasospastic angina, chronic stable angina and hypertension.

Zenusin Pharmacology

Nifedipine, the prototype of the dihydropyridine class of calcium-channel antagonists, is similar to other dihydropyridines including amlodipine, felodipine, isradipine, and nicardipine. Nifedipine is used to treat Prinzmetal's angina, hypertension, and other vascular disorders such as Raynaud's phenomenon. By blocking the calcium channels, Nifedipine inhibits the spasm of the coronary artery and dilates the systemic arteries, results in a increase of myocardial oxygen supply and a decrease in systemic blood pressure.

Zenusin Absorption

Rapidly and fully absorbed following oral administration.

Zenusin side effects and Toxicity

Symptoms of overdose include dizziness, drowsiness, nausea, severe drop in blood pressure, slurred speech, and weakness. LD50=494 mg/kg (orally in mice); LD50=1022 mg/kg (orally in rats)

Zenusin Patient Information

Zenusin Organisms Affected

Humans and other mammals