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Alfadal Brand names, Alfadal Analogs

Alfadal Brand Names Mixture

  • No information avaliable

Alfadal Chemical_Formula

C17H18N2O6

Alfadal RX_link

http://www.rxlist.com/cgi/generic2/nifedip.htm

Alfadal fda sheet

Alfadal FDA

Alfadal msds (material safety sheet)

Alfadal MSDS

Alfadal Synthesis Reference

Bossert, Vater, U.S. Pat. 3,485,847 (1969)

Alfadal Molecular Weight

346.335 g/mol

Alfadal Melting Point

172 - 174 oC

Alfadal H2O Solubility

Insoluble

Alfadal State

Solid

Alfadal LogP

2.343

Alfadal Dosage Forms

Capsule; Tablet; Tablet (extended-release)

Alfadal Indication

For the management of vasospastic angina, chronic stable angina and hypertension.

Alfadal Pharmacology

Nifedipine, the prototype of the dihydropyridine class of calcium-channel antagonists, is similar to other dihydropyridines including amlodipine, felodipine, isradipine, and nicardipine. Nifedipine is used to treat Prinzmetal's angina, hypertension, and other vascular disorders such as Raynaud's phenomenon. By blocking the calcium channels, Nifedipine inhibits the spasm of the coronary artery and dilates the systemic arteries, results in a increase of myocardial oxygen supply and a decrease in systemic blood pressure.

Alfadal Absorption

Rapidly and fully absorbed following oral administration.

Alfadal side effects and Toxicity

Symptoms of overdose include dizziness, drowsiness, nausea, severe drop in blood pressure, slurred speech, and weakness. LD50=494 mg/kg (orally in mice); LD50=1022 mg/kg (orally in rats)

Alfadal Patient Information

Alfadal Organisms Affected

Humans and other mammals