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Dilafed Brand names, Dilafed Analogs

Dilafed Brand Names Mixture

  • No information avaliable

Dilafed Chemical_Formula

C17H18N2O6

Dilafed RX_link

http://www.rxlist.com/cgi/generic2/nifedip.htm

Dilafed fda sheet

Dilafed FDA

Dilafed msds (material safety sheet)

Dilafed MSDS

Dilafed Synthesis Reference

Bossert, Vater, U.S. Pat. 3,485,847 (1969)

Dilafed Molecular Weight

346.335 g/mol

Dilafed Melting Point

172 - 174 oC

Dilafed H2O Solubility

Insoluble

Dilafed State

Solid

Dilafed LogP

2.343

Dilafed Dosage Forms

Capsule; Tablet; Tablet (extended-release)

Dilafed Indication

For the management of vasospastic angina, chronic stable angina and hypertension.

Dilafed Pharmacology

Nifedipine, the prototype of the dihydropyridine class of calcium-channel antagonists, is similar to other dihydropyridines including amlodipine, felodipine, isradipine, and nicardipine. Nifedipine is used to treat Prinzmetal's angina, hypertension, and other vascular disorders such as Raynaud's phenomenon. By blocking the calcium channels, Nifedipine inhibits the spasm of the coronary artery and dilates the systemic arteries, results in a increase of myocardial oxygen supply and a decrease in systemic blood pressure.

Dilafed Absorption

Rapidly and fully absorbed following oral administration.

Dilafed side effects and Toxicity

Symptoms of overdose include dizziness, drowsiness, nausea, severe drop in blood pressure, slurred speech, and weakness. LD50=494 mg/kg (orally in mice); LD50=1022 mg/kg (orally in rats)

Dilafed Patient Information

Dilafed Organisms Affected

Humans and other mammals