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Nifdemin Brand names, Nifdemin Analogs

Nifdemin Brand Names Mixture

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Nifdemin Chemical_Formula


Nifdemin RX_link

Nifdemin fda sheet

Nifdemin FDA

Nifdemin msds (material safety sheet)

Nifdemin MSDS

Nifdemin Synthesis Reference

Bossert, Vater, U.S. Pat. 3,485,847 (1969)

Nifdemin Molecular Weight

346.335 g/mol

Nifdemin Melting Point

172 - 174 oC

Nifdemin H2O Solubility


Nifdemin State


Nifdemin LogP


Nifdemin Dosage Forms

Capsule; Tablet; Tablet (extended-release)

Nifdemin Indication

For the management of vasospastic angina, chronic stable angina and hypertension.

Nifdemin Pharmacology

Nifedipine, the prototype of the dihydropyridine class of calcium-channel antagonists, is similar to other dihydropyridines including amlodipine, felodipine, isradipine, and nicardipine. Nifedipine is used to treat Prinzmetal's angina, hypertension, and other vascular disorders such as Raynaud's phenomenon. By blocking the calcium channels, Nifedipine inhibits the spasm of the coronary artery and dilates the systemic arteries, results in a increase of myocardial oxygen supply and a decrease in systemic blood pressure.

Nifdemin Absorption

Rapidly and fully absorbed following oral administration.

Nifdemin side effects and Toxicity

Symptoms of overdose include dizziness, drowsiness, nausea, severe drop in blood pressure, slurred speech, and weakness. LD50=494 mg/kg (orally in mice); LD50=1022 mg/kg (orally in rats)

Nifdemin Patient Information

Nifdemin Organisms Affected

Humans and other mammals