Alpha-Nifedipine Retard en es it fr

Alpha-Nifedipine Retard Brand names, Alpha-Nifedipine Retard Analogs

Alpha-Nifedipine Retard Brand Names Mixture

  • No information avaliable

Alpha-Nifedipine Retard Chemical_Formula

C17H18N2O6

Alpha-Nifedipine Retard RX_link

http://www.rxlist.com/cgi/generic2/nifedip.htm

Alpha-Nifedipine Retard fda sheet

Alpha-Nifedipine_Retard FDA

Alpha-Nifedipine Retard msds (material safety sheet)

Alpha-Nifedipine_Retard MSDS

Alpha-Nifedipine Retard Synthesis Reference

Bossert, Vater, U.S. Pat. 3,485,847 (1969)

Alpha-Nifedipine Retard Molecular Weight

346.335 g/mol

Alpha-Nifedipine Retard Melting Point

172 - 174 oC

Alpha-Nifedipine Retard H2O Solubility

Insoluble

Alpha-Nifedipine Retard State

Solid

Alpha-Nifedipine Retard LogP

2.343

Alpha-Nifedipine Retard Dosage Forms

Capsule; Tablet; Tablet (extended-release)

Alpha-Nifedipine Retard Indication

For the management of vasospastic angina, chronic stable angina and hypertension.

Alpha-Nifedipine Retard Pharmacology

Nifedipine, the prototype of the dihydropyridine class of calcium-channel antagonists, is similar to other dihydropyridines including amlodipine, felodipine, isradipine, and nicardipine. Nifedipine is used to treat Prinzmetal's angina, hypertension, and other vascular disorders such as Raynaud's phenomenon. By blocking the calcium channels, Nifedipine inhibits the spasm of the coronary artery and dilates the systemic arteries, results in a increase of myocardial oxygen supply and a decrease in systemic blood pressure.

Alpha-Nifedipine Retard Absorption

Rapidly and fully absorbed following oral administration.

Alpha-Nifedipine Retard side effects and Toxicity

Symptoms of overdose include dizziness, drowsiness, nausea, severe drop in blood pressure, slurred speech, and weakness. LD50=494 mg/kg (orally in mice); LD50=1022 mg/kg (orally in rats)

Alpha-Nifedipine Retard Patient Information

Alpha-Nifedipine Retard Organisms Affected

Humans and other mammals