Cardilate

Cardilate Brand names, Cardilate Analogs

Cardilate Brand Names Mixture

No information avaliable

Cardilate Chemical_Formula

C₁₇H₁₈N₂O₆

Cardilate RX_link

http://www.rxlist.com/cgi/generic2/nifedip.htm

Cardilate fda sheet

Cardilate FDA

Cardilate msds (material safety sheet)

Cardilate MSDS

Cardilate Synthesis Reference

Bossert, Vater, U.S. Pat. 3,485,847 (1969)

Cardilate Molecular Weight

346.335 g/mol

Cardilate Melting Point

172 - 174 ^oC

Cardilate H₂O Solubility

Insoluble

Cardilate State

Solid

Cardilate LogP

2.343

Cardilate Dosage Forms

Capsule; Tablet; Tablet (extended-release)

Cardilate Indication

For the management of vasospastic angina, chronic stable angina and hypertension.

Cardilate Pharmacology

Nifedipine, the prototype of the dihydropyridine class of calcium-channel antagonists, is similar to other dihydropyridines including amlodipine, felodipine, isradipine, and nicardipine. Nifedipine is used to treat Prinzmetal's angina, hypertension, and other vascular disorders such as Raynaud's phenomenon. By blocking the calcium channels, Nifedipine inhibits the spasm of the coronary artery and dilates the systemic arteries, results in a increase of myocardial oxygen supply and a decrease in systemic blood pressure.

Cardilate Absorption

Rapidly and fully absorbed following oral administration.

Cardilate side effects and Toxicity

Symptoms of overdose include dizziness, drowsiness, nausea, severe drop in blood pressure, slurred speech, and weakness. LD₅₀=494 mg/kg (orally in mice); LD₅₀=1022 mg/kg (orally in rats)

Cardilate Patient Information

Cardilate Organisms Affected

Humans and other mammals