Cardifen

Cardifen Brand names, Cardifen Analogs

Cardifen Brand Names Mixture

No information avaliable

Cardifen Chemical_Formula

C₁₇H₁₈N₂O₆

Cardifen RX_link

http://www.rxlist.com/cgi/generic2/nifedip.htm

Cardifen fda sheet

Cardifen FDA

Cardifen msds (material safety sheet)

Cardifen MSDS

Cardifen Synthesis Reference

Bossert, Vater, U.S. Pat. 3,485,847 (1969)

Cardifen Molecular Weight

346.335 g/mol

Cardifen Melting Point

172 - 174 ^oC

Cardifen H₂O Solubility

Insoluble

Cardifen State

Solid

Cardifen LogP

2.343

Cardifen Dosage Forms

Capsule; Tablet; Tablet (extended-release)

Cardifen Indication

For the management of vasospastic angina, chronic stable angina and hypertension.

Cardifen Pharmacology

Nifedipine, the prototype of the dihydropyridine class of calcium-channel antagonists, is similar to other dihydropyridines including amlodipine, felodipine, isradipine, and nicardipine. Nifedipine is used to treat Prinzmetal's angina, hypertension, and other vascular disorders such as Raynaud's phenomenon. By blocking the calcium channels, Nifedipine inhibits the spasm of the coronary artery and dilates the systemic arteries, results in a increase of myocardial oxygen supply and a decrease in systemic blood pressure.

Cardifen Absorption

Rapidly and fully absorbed following oral administration.

Cardifen side effects and Toxicity

Symptoms of overdose include dizziness, drowsiness, nausea, severe drop in blood pressure, slurred speech, and weakness. LD₅₀=494 mg/kg (orally in mice); LD₅₀=1022 mg/kg (orally in rats)

Cardifen Patient Information

Cardifen Organisms Affected

Humans and other mammals