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Calcilat Brand names, Calcilat Analogs

Calcilat Brand Names Mixture

  • No information avaliable

Calcilat Chemical_Formula

C17H18N2O6

Calcilat RX_link

http://www.rxlist.com/cgi/generic2/nifedip.htm

Calcilat fda sheet

Calcilat FDA

Calcilat msds (material safety sheet)

Calcilat MSDS

Calcilat Synthesis Reference

Bossert, Vater, U.S. Pat. 3,485,847 (1969)

Calcilat Molecular Weight

346.335 g/mol

Calcilat Melting Point

172 - 174 oC

Calcilat H2O Solubility

Insoluble

Calcilat State

Solid

Calcilat LogP

2.343

Calcilat Dosage Forms

Capsule; Tablet; Tablet (extended-release)

Calcilat Indication

For the management of vasospastic angina, chronic stable angina and hypertension.

Calcilat Pharmacology

Nifedipine, the prototype of the dihydropyridine class of calcium-channel antagonists, is similar to other dihydropyridines including amlodipine, felodipine, isradipine, and nicardipine. Nifedipine is used to treat Prinzmetal's angina, hypertension, and other vascular disorders such as Raynaud's phenomenon. By blocking the calcium channels, Nifedipine inhibits the spasm of the coronary artery and dilates the systemic arteries, results in a increase of myocardial oxygen supply and a decrease in systemic blood pressure.

Calcilat Absorption

Rapidly and fully absorbed following oral administration.

Calcilat side effects and Toxicity

Symptoms of overdose include dizziness, drowsiness, nausea, severe drop in blood pressure, slurred speech, and weakness. LD50=494 mg/kg (orally in mice); LD50=1022 mg/kg (orally in rats)

Calcilat Patient Information

Calcilat Organisms Affected

Humans and other mammals