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Hadipin Brand names, Hadipin Analogs

Hadipin Brand Names Mixture

  • No information avaliable

Hadipin Chemical_Formula

C17H18N2O6

Hadipin RX_link

http://www.rxlist.com/cgi/generic2/nifedip.htm

Hadipin fda sheet

Hadipin FDA

Hadipin msds (material safety sheet)

Hadipin MSDS

Hadipin Synthesis Reference

Bossert, Vater, U.S. Pat. 3,485,847 (1969)

Hadipin Molecular Weight

346.335 g/mol

Hadipin Melting Point

172 - 174 oC

Hadipin H2O Solubility

Insoluble

Hadipin State

Solid

Hadipin LogP

2.343

Hadipin Dosage Forms

Capsule; Tablet; Tablet (extended-release)

Hadipin Indication

For the management of vasospastic angina, chronic stable angina and hypertension.

Hadipin Pharmacology

Nifedipine, the prototype of the dihydropyridine class of calcium-channel antagonists, is similar to other dihydropyridines including amlodipine, felodipine, isradipine, and nicardipine. Nifedipine is used to treat Prinzmetal's angina, hypertension, and other vascular disorders such as Raynaud's phenomenon. By blocking the calcium channels, Nifedipine inhibits the spasm of the coronary artery and dilates the systemic arteries, results in a increase of myocardial oxygen supply and a decrease in systemic blood pressure.

Hadipin Absorption

Rapidly and fully absorbed following oral administration.

Hadipin side effects and Toxicity

Symptoms of overdose include dizziness, drowsiness, nausea, severe drop in blood pressure, slurred speech, and weakness. LD50=494 mg/kg (orally in mice); LD50=1022 mg/kg (orally in rats)

Hadipin Patient Information

Hadipin Organisms Affected

Humans and other mammals