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Coracten Brand names, Coracten Analogs

Coracten Brand Names Mixture

  • No information avaliable

Coracten Chemical_Formula

C17H18N2O6

Coracten RX_link

http://www.rxlist.com/cgi/generic2/nifedip.htm

Coracten fda sheet

Coracten FDA

Coracten msds (material safety sheet)

Coracten MSDS

Coracten Synthesis Reference

Bossert, Vater, U.S. Pat. 3,485,847 (1969)

Coracten Molecular Weight

346.335 g/mol

Coracten Melting Point

172 - 174 oC

Coracten H2O Solubility

Insoluble

Coracten State

Solid

Coracten LogP

2.343

Coracten Dosage Forms

Capsule; Tablet; Tablet (extended-release)

Coracten Indication

For the management of vasospastic angina, chronic stable angina and hypertension.

Coracten Pharmacology

Nifedipine, the prototype of the dihydropyridine class of calcium-channel antagonists, is similar to other dihydropyridines including amlodipine, felodipine, isradipine, and nicardipine. Nifedipine is used to treat Prinzmetal's angina, hypertension, and other vascular disorders such as Raynaud's phenomenon. By blocking the calcium channels, Nifedipine inhibits the spasm of the coronary artery and dilates the systemic arteries, results in a increase of myocardial oxygen supply and a decrease in systemic blood pressure.

Coracten Absorption

Rapidly and fully absorbed following oral administration.

Coracten side effects and Toxicity

Symptoms of overdose include dizziness, drowsiness, nausea, severe drop in blood pressure, slurred speech, and weakness. LD50=494 mg/kg (orally in mice); LD50=1022 mg/kg (orally in rats)

Coracten Patient Information

Coracten Organisms Affected

Humans and other mammals