Niphedipine
Niphedipine Brand names, Niphedipine Analogs
- Adalat
- Adalat 10
- Adalat 20
- Adalat 5
- Adalat CC
- Adalat CR
- Adalat Crono
- Adalat Ft
- Adalat Gits
- Adalat Gits 30
- Adalat LA
- Adalat LP
- Adalat Oros
- Adalat PA
- Adalat Retard
- Adalate
- Adapine
- Adapress
- Alat
- Aldipin
- Alfadal
- Alonix
- Alonix S
- Alpha-Nifedipine Retard
- Angipec
- Anifed
- Anpine
- Apo-Nifed
- Aprical
- Bonacid
- Calcibloc
- Calcigard
- Calcilat
- Camont
- Cardifen
- Cardilat
- Cardilate
- Cardionorm
- Chronadalate
- Chronadalate Lp
- Citilat
- Coracten
- Coral
- Cordafen
- Cordaflex
- Cordalat
- Cordicant
- Cordilan
- Cordipin
- Corinfar
- Corotrend
- Corynphar
- Depin
- Dignokonstant
- Dilafed
- Dilcor
- Dipinkor
- Duranifin
- Ecodipi
- Ecodipin
- Ecodipin E
- Fedcor
- Fedcor Retard
- Fenamon
- Fenamon Sr
- Fenihidin
- Fenihidine
- Glopir
- Hadipin
- Hexadilat
- Introcar
- Kordafen
- Macorel
- Megalat
- Myogard
- N1fedilat
- Nedipin
- Nicardia
- Nifangin
- Nifar
- Nifdemin
- Nifebene
- Nifecard
- Nifecor
- Nifedepat
- Nifedicor
- Nifedin
- Nifedine
- Nifedipine Retard
- Nifedipres
- Nifedirex LP
- Nifelan
- Nifelat
- Nifelat Q
- Nifelate
- Nifensar XL
- Nificard
- Nifidine
- Nifipen
- Niphedipine
- Orix
- Oxcord
- Pidilat
- Procardia
- Procardia XL
- Sepamit
- Tibricol
- Zenusin
Niphedipine Brand Names Mixture
- No information avaliable
Niphedipine Chemical_Formula
C17H18N2O6
Niphedipine RX_link
http://www.rxlist.com/cgi/generic2/nifedip.htm
Niphedipine fda sheet
Niphedipine msds (material safety sheet)
Niphedipine Synthesis Reference
Bossert, Vater, U.S. Pat. 3,485,847 (1969)
Niphedipine Molecular Weight
346.335 g/mol
Niphedipine Melting Point
172 - 174 oC
Niphedipine H2O Solubility
Insoluble
Niphedipine State
Solid
Niphedipine LogP
2.343
Niphedipine Dosage Forms
Capsule; Tablet; Tablet (extended-release)
Niphedipine Indication
For the management of vasospastic angina, chronic stable angina and hypertension.
Niphedipine Pharmacology
Nifedipine, the prototype of the dihydropyridine class of calcium-channel antagonists, is similar to other dihydropyridines including amlodipine, felodipine, isradipine, and nicardipine. Nifedipine is used to treat Prinzmetal's angina, hypertension, and other vascular disorders such as Raynaud's phenomenon. By blocking the calcium channels, Nifedipine inhibits the spasm of the coronary artery and dilates the systemic arteries, results in a increase of myocardial oxygen supply and a decrease in systemic blood pressure.
Niphedipine Absorption
Rapidly and fully absorbed following oral administration.
Niphedipine side effects and Toxicity
Symptoms of overdose include dizziness, drowsiness, nausea, severe drop in blood pressure, slurred speech, and weakness. LD50=494 mg/kg (orally in mice); LD50=1022 mg/kg (orally in rats)
Niphedipine Patient Information
Niphedipine Organisms Affected
Humans and other mammals
