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Calcigard Brand names, Calcigard Analogs

Calcigard Brand Names Mixture

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Calcigard Chemical_Formula


Calcigard RX_link

Calcigard fda sheet

Calcigard FDA

Calcigard msds (material safety sheet)

Calcigard MSDS

Calcigard Synthesis Reference

Bossert, Vater, U.S. Pat. 3,485,847 (1969)

Calcigard Molecular Weight

346.335 g/mol

Calcigard Melting Point

172 - 174 oC

Calcigard H2O Solubility


Calcigard State


Calcigard LogP


Calcigard Dosage Forms

Capsule; Tablet; Tablet (extended-release)

Calcigard Indication

For the management of vasospastic angina, chronic stable angina and hypertension.

Calcigard Pharmacology

Nifedipine, the prototype of the dihydropyridine class of calcium-channel antagonists, is similar to other dihydropyridines including amlodipine, felodipine, isradipine, and nicardipine. Nifedipine is used to treat Prinzmetal's angina, hypertension, and other vascular disorders such as Raynaud's phenomenon. By blocking the calcium channels, Nifedipine inhibits the spasm of the coronary artery and dilates the systemic arteries, results in a increase of myocardial oxygen supply and a decrease in systemic blood pressure.

Calcigard Absorption

Rapidly and fully absorbed following oral administration.

Calcigard side effects and Toxicity

Symptoms of overdose include dizziness, drowsiness, nausea, severe drop in blood pressure, slurred speech, and weakness. LD50=494 mg/kg (orally in mice); LD50=1022 mg/kg (orally in rats)

Calcigard Patient Information

Calcigard Organisms Affected

Humans and other mammals