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Ecodipin Brand names, Ecodipin Analogs

Ecodipin Brand Names Mixture

  • No information avaliable

Ecodipin Chemical_Formula

C17H18N2O6

Ecodipin RX_link

http://www.rxlist.com/cgi/generic2/nifedip.htm

Ecodipin fda sheet

Ecodipin FDA

Ecodipin msds (material safety sheet)

Ecodipin MSDS

Ecodipin Synthesis Reference

Bossert, Vater, U.S. Pat. 3,485,847 (1969)

Ecodipin Molecular Weight

346.335 g/mol

Ecodipin Melting Point

172 - 174 oC

Ecodipin H2O Solubility

Insoluble

Ecodipin State

Solid

Ecodipin LogP

2.343

Ecodipin Dosage Forms

Capsule; Tablet; Tablet (extended-release)

Ecodipin Indication

For the management of vasospastic angina, chronic stable angina and hypertension.

Ecodipin Pharmacology

Nifedipine, the prototype of the dihydropyridine class of calcium-channel antagonists, is similar to other dihydropyridines including amlodipine, felodipine, isradipine, and nicardipine. Nifedipine is used to treat Prinzmetal's angina, hypertension, and other vascular disorders such as Raynaud's phenomenon. By blocking the calcium channels, Nifedipine inhibits the spasm of the coronary artery and dilates the systemic arteries, results in a increase of myocardial oxygen supply and a decrease in systemic blood pressure.

Ecodipin Absorption

Rapidly and fully absorbed following oral administration.

Ecodipin side effects and Toxicity

Symptoms of overdose include dizziness, drowsiness, nausea, severe drop in blood pressure, slurred speech, and weakness. LD50=494 mg/kg (orally in mice); LD50=1022 mg/kg (orally in rats)

Ecodipin Patient Information

Ecodipin Organisms Affected

Humans and other mammals