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Glopir Brand names, Glopir Analogs

Glopir Brand Names Mixture

  • No information avaliable

Glopir Chemical_Formula

C17H18N2O6

Glopir RX_link

http://www.rxlist.com/cgi/generic2/nifedip.htm

Glopir fda sheet

Glopir FDA

Glopir msds (material safety sheet)

Glopir MSDS

Glopir Synthesis Reference

Bossert, Vater, U.S. Pat. 3,485,847 (1969)

Glopir Molecular Weight

346.335 g/mol

Glopir Melting Point

172 - 174 oC

Glopir H2O Solubility

Insoluble

Glopir State

Solid

Glopir LogP

2.343

Glopir Dosage Forms

Capsule; Tablet; Tablet (extended-release)

Glopir Indication

For the management of vasospastic angina, chronic stable angina and hypertension.

Glopir Pharmacology

Nifedipine, the prototype of the dihydropyridine class of calcium-channel antagonists, is similar to other dihydropyridines including amlodipine, felodipine, isradipine, and nicardipine. Nifedipine is used to treat Prinzmetal's angina, hypertension, and other vascular disorders such as Raynaud's phenomenon. By blocking the calcium channels, Nifedipine inhibits the spasm of the coronary artery and dilates the systemic arteries, results in a increase of myocardial oxygen supply and a decrease in systemic blood pressure.

Glopir Absorption

Rapidly and fully absorbed following oral administration.

Glopir side effects and Toxicity

Symptoms of overdose include dizziness, drowsiness, nausea, severe drop in blood pressure, slurred speech, and weakness. LD50=494 mg/kg (orally in mice); LD50=1022 mg/kg (orally in rats)

Glopir Patient Information

Glopir Organisms Affected

Humans and other mammals