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Bonacid Brand names, Bonacid Analogs

Bonacid Brand Names Mixture

  • No information avaliable

Bonacid Chemical_Formula

C17H18N2O6

Bonacid RX_link

http://www.rxlist.com/cgi/generic2/nifedip.htm

Bonacid fda sheet

Bonacid FDA

Bonacid msds (material safety sheet)

Bonacid MSDS

Bonacid Synthesis Reference

Bossert, Vater, U.S. Pat. 3,485,847 (1969)

Bonacid Molecular Weight

346.335 g/mol

Bonacid Melting Point

172 - 174 oC

Bonacid H2O Solubility

Insoluble

Bonacid State

Solid

Bonacid LogP

2.343

Bonacid Dosage Forms

Capsule; Tablet; Tablet (extended-release)

Bonacid Indication

For the management of vasospastic angina, chronic stable angina and hypertension.

Bonacid Pharmacology

Nifedipine, the prototype of the dihydropyridine class of calcium-channel antagonists, is similar to other dihydropyridines including amlodipine, felodipine, isradipine, and nicardipine. Nifedipine is used to treat Prinzmetal's angina, hypertension, and other vascular disorders such as Raynaud's phenomenon. By blocking the calcium channels, Nifedipine inhibits the spasm of the coronary artery and dilates the systemic arteries, results in a increase of myocardial oxygen supply and a decrease in systemic blood pressure.

Bonacid Absorption

Rapidly and fully absorbed following oral administration.

Bonacid side effects and Toxicity

Symptoms of overdose include dizziness, drowsiness, nausea, severe drop in blood pressure, slurred speech, and weakness. LD50=494 mg/kg (orally in mice); LD50=1022 mg/kg (orally in rats)

Bonacid Patient Information

Bonacid Organisms Affected

Humans and other mammals