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Nifecor Brand names, Nifecor Analogs

Nifecor Brand Names Mixture

  • No information avaliable

Nifecor Chemical_Formula

C17H18N2O6

Nifecor RX_link

http://www.rxlist.com/cgi/generic2/nifedip.htm

Nifecor fda sheet

Nifecor FDA

Nifecor msds (material safety sheet)

Nifecor MSDS

Nifecor Synthesis Reference

Bossert, Vater, U.S. Pat. 3,485,847 (1969)

Nifecor Molecular Weight

346.335 g/mol

Nifecor Melting Point

172 - 174 oC

Nifecor H2O Solubility

Insoluble

Nifecor State

Solid

Nifecor LogP

2.343

Nifecor Dosage Forms

Capsule; Tablet; Tablet (extended-release)

Nifecor Indication

For the management of vasospastic angina, chronic stable angina and hypertension.

Nifecor Pharmacology

Nifedipine, the prototype of the dihydropyridine class of calcium-channel antagonists, is similar to other dihydropyridines including amlodipine, felodipine, isradipine, and nicardipine. Nifedipine is used to treat Prinzmetal's angina, hypertension, and other vascular disorders such as Raynaud's phenomenon. By blocking the calcium channels, Nifedipine inhibits the spasm of the coronary artery and dilates the systemic arteries, results in a increase of myocardial oxygen supply and a decrease in systemic blood pressure.

Nifecor Absorption

Rapidly and fully absorbed following oral administration.

Nifecor side effects and Toxicity

Symptoms of overdose include dizziness, drowsiness, nausea, severe drop in blood pressure, slurred speech, and weakness. LD50=494 mg/kg (orally in mice); LD50=1022 mg/kg (orally in rats)

Nifecor Patient Information

Nifecor Organisms Affected

Humans and other mammals