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Ecodipi Brand names, Ecodipi Analogs

Ecodipi Brand Names Mixture

  • No information avaliable

Ecodipi Chemical_Formula

C17H18N2O6

Ecodipi RX_link

http://www.rxlist.com/cgi/generic2/nifedip.htm

Ecodipi fda sheet

Ecodipi FDA

Ecodipi msds (material safety sheet)

Ecodipi MSDS

Ecodipi Synthesis Reference

Bossert, Vater, U.S. Pat. 3,485,847 (1969)

Ecodipi Molecular Weight

346.335 g/mol

Ecodipi Melting Point

172 - 174 oC

Ecodipi H2O Solubility

Insoluble

Ecodipi State

Solid

Ecodipi LogP

2.343

Ecodipi Dosage Forms

Capsule; Tablet; Tablet (extended-release)

Ecodipi Indication

For the management of vasospastic angina, chronic stable angina and hypertension.

Ecodipi Pharmacology

Nifedipine, the prototype of the dihydropyridine class of calcium-channel antagonists, is similar to other dihydropyridines including amlodipine, felodipine, isradipine, and nicardipine. Nifedipine is used to treat Prinzmetal's angina, hypertension, and other vascular disorders such as Raynaud's phenomenon. By blocking the calcium channels, Nifedipine inhibits the spasm of the coronary artery and dilates the systemic arteries, results in a increase of myocardial oxygen supply and a decrease in systemic blood pressure.

Ecodipi Absorption

Rapidly and fully absorbed following oral administration.

Ecodipi side effects and Toxicity

Symptoms of overdose include dizziness, drowsiness, nausea, severe drop in blood pressure, slurred speech, and weakness. LD50=494 mg/kg (orally in mice); LD50=1022 mg/kg (orally in rats)

Ecodipi Patient Information

Ecodipi Organisms Affected

Humans and other mammals