Nicardia Brand names, Nicardia Analogs
Nicardia Brand Names Mixture
Nicardia fda sheet
Nicardia msds (material safety sheet)
Nicardia Synthesis Reference
Bossert, Vater, U.S. Pat. 3,485,847 (1969)
Nicardia Molecular Weight
Nicardia Melting Point
172 - 174 oC
Nicardia H2O Solubility
Nicardia Dosage Forms
Capsule; Tablet; Tablet (extended-release)
For the management of vasospastic angina, chronic stable angina and hypertension.
Nifedipine, the prototype of the dihydropyridine class of calcium-channel antagonists, is similar to other dihydropyridines including amlodipine, felodipine, isradipine, and nicardipine. Nifedipine is used to treat Prinzmetal's angina, hypertension, and other vascular disorders such as Raynaud's phenomenon. By blocking the calcium channels, Nifedipine inhibits the spasm of the coronary artery and dilates the systemic arteries, results in a increase of myocardial oxygen supply and a decrease in systemic blood pressure.
Rapidly and fully absorbed following oral administration.
Nicardia side effects and Toxicity
Symptoms of overdose include dizziness, drowsiness, nausea, severe drop in blood pressure, slurred speech, and weakness. LD50=494 mg/kg (orally in mice); LD50=1022 mg/kg (orally in rats)
Nicardia Patient Information
Nicardia Organisms Affected
Humans and other mammals