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Nicardia
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Nicardia Brand names, Nicardia Analogs

Nicardia Brand Names Mixture

  • No information avaliable

Nicardia Chemical_Formula

C17H18N2O6

Nicardia RX_link

http://www.rxlist.com/cgi/generic2/nifedip.htm

Nicardia fda sheet

Nicardia FDA

Nicardia msds (material safety sheet)

Nicardia MSDS

Nicardia Synthesis Reference

Bossert, Vater, U.S. Pat. 3,485,847 (1969)

Nicardia Molecular Weight

346.335 g/mol

Nicardia Melting Point

172 - 174 oC

Nicardia H2O Solubility

Insoluble

Nicardia State

Solid

Nicardia LogP

2.343

Nicardia Dosage Forms

Capsule; Tablet; Tablet (extended-release)

Nicardia Indication

For the management of vasospastic angina, chronic stable angina and hypertension.

Nicardia Pharmacology

Nifedipine, the prototype of the dihydropyridine class of calcium-channel antagonists, is similar to other dihydropyridines including amlodipine, felodipine, isradipine, and nicardipine. Nifedipine is used to treat Prinzmetal's angina, hypertension, and other vascular disorders such as Raynaud's phenomenon. By blocking the calcium channels, Nifedipine inhibits the spasm of the coronary artery and dilates the systemic arteries, results in a increase of myocardial oxygen supply and a decrease in systemic blood pressure.

Nicardia Absorption

Rapidly and fully absorbed following oral administration.

Nicardia side effects and Toxicity

Symptoms of overdose include dizziness, drowsiness, nausea, severe drop in blood pressure, slurred speech, and weakness. LD50=494 mg/kg (orally in mice); LD50=1022 mg/kg (orally in rats)

Nicardia Patient Information

Nicardia Organisms Affected

Humans and other mammals