Adalat LP en es it fr

Adalat LP Brand names, Adalat LP Analogs

Adalat LP Brand Names Mixture

  • No information avaliable

Adalat LP Chemical_Formula

C17H18N2O6

Adalat LP RX_link

http://www.rxlist.com/cgi/generic2/nifedip.htm

Adalat LP fda sheet

Adalat_LP FDA

Adalat LP msds (material safety sheet)

Adalat_LP MSDS

Adalat LP Synthesis Reference

Bossert, Vater, U.S. Pat. 3,485,847 (1969)

Adalat LP Molecular Weight

346.335 g/mol

Adalat LP Melting Point

172 - 174 oC

Adalat LP H2O Solubility

Insoluble

Adalat LP State

Solid

Adalat LP LogP

2.343

Adalat LP Dosage Forms

Capsule; Tablet; Tablet (extended-release)

Adalat LP Indication

For the management of vasospastic angina, chronic stable angina and hypertension.

Adalat LP Pharmacology

Nifedipine, the prototype of the dihydropyridine class of calcium-channel antagonists, is similar to other dihydropyridines including amlodipine, felodipine, isradipine, and nicardipine. Nifedipine is used to treat Prinzmetal's angina, hypertension, and other vascular disorders such as Raynaud's phenomenon. By blocking the calcium channels, Nifedipine inhibits the spasm of the coronary artery and dilates the systemic arteries, results in a increase of myocardial oxygen supply and a decrease in systemic blood pressure.

Adalat LP Absorption

Rapidly and fully absorbed following oral administration.

Adalat LP side effects and Toxicity

Symptoms of overdose include dizziness, drowsiness, nausea, severe drop in blood pressure, slurred speech, and weakness. LD50=494 mg/kg (orally in mice); LD50=1022 mg/kg (orally in rats)

Adalat LP Patient Information

Adalat LP Organisms Affected

Humans and other mammals