Clofibrat
Brand names,
Clofibrat
Analogs
Clofibrat
Brand Names Mixture
Clofibrat
Chemical_Formula
C26H28N2
Clofibrat
RX_link
No information avaliable
Clofibrat
fda sheet
Clofibrat
msds (material safety sheet)
Clofibrat
Synthesis Reference
No information avaliable
Clofibrat
Molecular Weight
368.514 g/mol
Clofibrat
Melting Point
No information avaliable
Clofibrat
H2O Solubility
750 mg/L
Clofibrat
State
Solid
Clofibrat
LogP
5.63
Clofibrat
Dosage Forms
No information avaliable
Clofibrat
Indication
For the treatment of vertigo/meniere's disease, nausea and vomiting, motion sickness and also useful for vestibular symptoms of other origins.
Clofibrat
Pharmacology
Cinnarizine is an antihistamine and a calcium channel blocker. Histamines mediate a number of activities such as contraction of smooth muscle of the airways and gastrointestinal tract, vasodilatation, cardiac stimulation, secretion of gastric acid, promotion of interleukin release and chemotaxis of eosinophils and mast cells. Competitive antagonists at histamine H1 receptors may be divided into first (sedating) and second (non-sedating) generation agents. Some, such as Cinnarizine also block muscarinic acetylcholine receptors and are used as anti-emetic agents. Cinnarizine through its calcium channel blocking ability also inhibits stimulation of the vestibular system.
Clofibrat
Absorption
No information avaliable
Clofibrat
side effects and Toxicity
No information avaliable
Clofibrat
Patient Information
No information avaliable
Clofibrat
Organisms Affected
Humans and other mammals