Dimitronal
Brand names,
Dimitronal
Analogs
Dimitronal
Brand Names Mixture
Dimitronal
Chemical_Formula
C26H28N2
Dimitronal
RX_link
No information avaliable
Dimitronal
fda sheet
Dimitronal
msds (material safety sheet)
Dimitronal
Synthesis Reference
No information avaliable
Dimitronal
Molecular Weight
368.514 g/mol
Dimitronal
Melting Point
No information avaliable
Dimitronal
H2O Solubility
750 mg/L
Dimitronal
State
Solid
Dimitronal
LogP
5.63
Dimitronal
Dosage Forms
No information avaliable
Dimitronal
Indication
For the treatment of vertigo/meniere's disease, nausea and vomiting, motion sickness and also useful for vestibular symptoms of other origins.
Dimitronal
Pharmacology
Cinnarizine is an antihistamine and a calcium channel blocker. Histamines mediate a number of activities such as contraction of smooth muscle of the airways and gastrointestinal tract, vasodilatation, cardiac stimulation, secretion of gastric acid, promotion of interleukin release and chemotaxis of eosinophils and mast cells. Competitive antagonists at histamine H1 receptors may be divided into first (sedating) and second (non-sedating) generation agents. Some, such as Cinnarizine also block muscarinic acetylcholine receptors and are used as anti-emetic agents. Cinnarizine through its calcium channel blocking ability also inhibits stimulation of the vestibular system.
Dimitronal
Absorption
No information avaliable
Dimitronal
side effects and Toxicity
No information avaliable
Dimitronal
Patient Information
No information avaliable
Dimitronal
Organisms Affected
Humans and other mammals