Corathiem
Brand names,
Corathiem
Analogs
Corathiem
Brand Names Mixture
Corathiem
Chemical_Formula
C26H28N2
Corathiem
RX_link
No information avaliable
Corathiem
fda sheet
Corathiem
msds (material safety sheet)
Corathiem
Synthesis Reference
No information avaliable
Corathiem
Molecular Weight
368.514 g/mol
Corathiem
Melting Point
No information avaliable
Corathiem
H2O Solubility
750 mg/L
Corathiem
State
Solid
Corathiem
LogP
5.63
Corathiem
Dosage Forms
No information avaliable
Corathiem
Indication
For the treatment of vertigo/meniere's disease, nausea and vomiting, motion sickness and also useful for vestibular symptoms of other origins.
Corathiem
Pharmacology
Cinnarizine is an antihistamine and a calcium channel blocker. Histamines mediate a number of activities such as contraction of smooth muscle of the airways and gastrointestinal tract, vasodilatation, cardiac stimulation, secretion of gastric acid, promotion of interleukin release and chemotaxis of eosinophils and mast cells. Competitive antagonists at histamine H1 receptors may be divided into first (sedating) and second (non-sedating) generation agents. Some, such as Cinnarizine also block muscarinic acetylcholine receptors and are used as anti-emetic agents. Cinnarizine through its calcium channel blocking ability also inhibits stimulation of the vestibular system.
Corathiem
Absorption
No information avaliable
Corathiem
side effects and Toxicity
No information avaliable
Corathiem
Patient Information
No information avaliable
Corathiem
Organisms Affected
Humans and other mammals