Stutgin
Brand names,
Stutgin
Analogs
Stutgin
Brand Names Mixture
Stutgin
Chemical_Formula
C26H28N2
Stutgin
RX_link
No information avaliable
Stutgin
fda sheet
Stutgin
msds (material safety sheet)
Stutgin
Synthesis Reference
No information avaliable
Stutgin
Molecular Weight
368.514 g/mol
Stutgin
Melting Point
No information avaliable
Stutgin
H2O Solubility
750 mg/L
Stutgin
State
Solid
Stutgin
LogP
5.63
Stutgin
Dosage Forms
No information avaliable
Stutgin
Indication
For the treatment of vertigo/meniere's disease, nausea and vomiting, motion sickness and also useful for vestibular symptoms of other origins.
Stutgin
Pharmacology
Cinnarizine is an antihistamine and a calcium channel blocker. Histamines mediate a number of activities such as contraction of smooth muscle of the airways and gastrointestinal tract, vasodilatation, cardiac stimulation, secretion of gastric acid, promotion of interleukin release and chemotaxis of eosinophils and mast cells. Competitive antagonists at histamine H1 receptors may be divided into first (sedating) and second (non-sedating) generation agents. Some, such as Cinnarizine also block muscarinic acetylcholine receptors and are used as anti-emetic agents. Cinnarizine through its calcium channel blocking ability also inhibits stimulation of the vestibular system.
Stutgin
Absorption
No information avaliable
Stutgin
side effects and Toxicity
No information avaliable
Stutgin
Patient Information
No information avaliable
Stutgin
Organisms Affected
Humans and other mammals